The future of autoimmune disease.
The recently introduced thesis, about a gene suspected to be the underlying cause behind the immune response, which causes autoimmune conditions, could be the road to finding the cure that everyone has long awaited.
The gene in question, which is called the VGLL3 gene; vestigial-like family member 3 gene, per their research, seems to be the regulator of immune response genes. These genes are said to be more common in women and is being suggested to be the reason why women are more prone to autoimmune disease.
Research being conducted on these transgenic mice, has revealed that having excess VGLL3 genes in skin cells pushes the immune system into overdrive; which leads to the self-attacking immune response. The scientists already proved that having autoimmune conditions like lupus; causes genes of similar expressions in the body to alter. Testing this theory on the mice, they realized that the increase in VGLL3 , wreaked havoc in the mice. Their skin became scaly and raw and the mice also produced antibodies against their own tissues. Some of these antibodies the mice produced are similar, to those that can destroy the kidneys of lupus patients.
Well, there is certainly hope for anyone one out there who might have autoimmune disease and is going through so much.
"If the results confirm a hypothesis, you have made a discovery'
If the results are contrary to the hypothesis, you have made a discovery"- Enrico Fermi
" The joy of discovery, is certainly the loveliest that the mind of man can ever feel."-Claude Bernard
The gene in question, which is called the VGLL3 gene; vestigial-like family member 3 gene, per their research, seems to be the regulator of immune response genes. These genes are said to be more common in women and is being suggested to be the reason why women are more prone to autoimmune disease.
Research being conducted on these transgenic mice, has revealed that having excess VGLL3 genes in skin cells pushes the immune system into overdrive; which leads to the self-attacking immune response. The scientists already proved that having autoimmune conditions like lupus; causes genes of similar expressions in the body to alter. Testing this theory on the mice, they realized that the increase in VGLL3 , wreaked havoc in the mice. Their skin became scaly and raw and the mice also produced antibodies against their own tissues. Some of these antibodies the mice produced are similar, to those that can destroy the kidneys of lupus patients.
Well, there is certainly hope for anyone one out there who might have autoimmune disease and is going through so much.
"If the results confirm a hypothesis, you have made a discovery'
If the results are contrary to the hypothesis, you have made a discovery"- Enrico Fermi
" The joy of discovery, is certainly the loveliest that the mind of man can ever feel."-Claude Bernard
